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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: C2 domain-containing protein 5

UniprotKB/SwissProt ID: Q86YS7 (Q86YS7)

Gene Name: C2CD5

Organism: Homo sapiens (Human)

Function: Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasmic vesicle membrane. Cytoplasm, cell cortex. Cell membrane. Cell projection, ruffle

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR037785 C2_C2CD5
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR038983 C2CD5
IPR056430 C2CD5_YbjQ-like_dom
IPR056431 C2CD5_YbjQ-rel_dom

The S-nitrosylation sites of Q86YS7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 449 RFLQDGTVEG C LEQRLEENLP   
2 867 GNFRNRSAPP C ANSTVGVVKM   
3 989 VVSSQQPTTN C QSSCTEGEVT