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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Transcriptional repressor p66-alpha

UniprotKB/SwissProt ID: Q86YP4 (Q86YP4)

Gene Name: GATAD2A

Organism: Homo sapiens (Human)

Function: Transcriptional repressor (PubMed:12183469, PubMed:16415179). Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:16428440, PubMed:28977666). Enhances MBD2-mediated repression (PubMed:12183469, PubMed:16415179). Efficient repression requires the presence of GATAD2B (PubMed:16415179)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus speckle. Nucleus. Chromosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR040386 P66
IPR032346 P66_CC
IPR000679 Znf_GATA

The S-nitrosylation sites of Q86YP4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 417 ATVLSREPYM C AQCKTDFTCR