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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Syntaxin-12

UniprotKB/SwissProt ID: Q86Y82 (Q86Y82)

Gene Name: STX12

Organism: Homo sapiens (Human)

Function: SNARE promoting fusion of transport vesicles with target membranes. Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endosome membrane. Golgi apparatus membrane. Endomembrane system. Early endosome membrane. Recycling endosome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR010989 SNARE
IPR045242 Syntaxin
IPR006012 Syntaxin/epimorphin_CS
IPR006011 Syntaxin_N
IPR000727 T_SNARE_dom

The S-nitrosylation sites of Q86Y82

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 29 LRDFSSIIQT C SGNIQRISQA