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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Regulator of DNA class I crossover intermediates 1

UniprotKB/SwissProt ID: Q86WS4 (Q86WS4)

Gene Name: REDIC1

Organism: Homo sapiens (Human)

Function: Involved in recombination, probably acting by stabilizing recombination intermediates during meiotic crossover formation. Required for normal germline development and fertility. Required for meiotic progression, complete chromosomal synapsis and crossover formation. Binds double-stranded DNA. However, also binds branched DNA molecules, such as those containing a D-loop or Holliday junction structure. Probably not required for formation of DNA double-strand breaks (DSBs). Also binds RNA in an RNA structure-independent manner, with a preference for binding 3'-UTR regions of mRNAs; may stabilize bound RNAs

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Chromosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027883 Redic1-like

The S-nitrosylation sites of Q86WS4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 99 HNLELTMSPH C VPSKLCLDDT