Protein Name:
Fermitin family homolog 3
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UniprotKB/SwissProt ID: Q86UX7 (Q86UX7)
Gene Name:
FERMT3
Organism: Homo sapiens (Human)
Function: Plays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity) Isoform 2 may act as a repressor of NF-kappa-B and apoptosis
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell projection, podosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q86UX7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
407 |
DPIQQLNLKG C EVVPDVNVSG |
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