Protein Name:
Suppressor APC domain-containing protein 2
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UniprotKB/SwissProt ID: Q86UD0 (Q86UD0)
Gene Name:
SAPCD2
Organism: Homo sapiens (Human)
Function: Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions (By similarity). Negatively regulates the mitotic apical cortex localization of GPSM2 (PubMed:26766442). Involved also in positive regulation of cell proliferation and tumor cell growth (PubMed:23576022, PubMed:23704824)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Cytoplasm, cell cortex. Apical cell membrane. Cell junction, tight junction
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR026828
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Suppressor_APCD_1/2 |
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The S-nitrosylation sites of Q86UD0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
195 |
SSSADAGAVA C RALEADSGDA |
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