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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Hsc70-interacting protein 2

UniprotKB/SwissProt ID: Q86DS1 (Q86DS1)

Gene Name: HIP-R

Organism: Drosophila melanogaster (Fruit fly)

Function: One HIP oligomer binds the ATPase domains of at least two Hsc70 molecules dependent on activation of the Hsc70 ATPase by Hsp40. Stabilizes the ADP state of Hsc70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of Hsc70 with various target proteins (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR034649 Hip_N
IPR006636 STI1_HS-bd
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_rpt