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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Peroxisomal OPC-8:0-CoA ligase 1

UniprotKB/SwissProt ID: Q84P21 (Q84P21)

Gene Name: 4CLL5

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Contributes to jasmonic acid biosynthesis by initiating the beta-oxidative chain shortening of its precursors (PubMed:16963437, PubMed:18267944). Converts 12-oxo-phytodienoic acid (OPDA) and 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid (OPC-8:0) into OPDA-CoA and OPC-8:0-CoA, respectively (PubMed:16963437, PubMed:18267944). Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioester (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Peroxisome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR025110 AMP-bd_C
IPR045851 AMP-bd_C_sf
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_synth/lig_dom
IPR042099 ANL_N_sf

The S-nitrosylation sites of Q84P21

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 73 LWRAVESVAD C LSEIGIRKGH