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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Acylamino-acid-releasing enzyme

UniprotKB/SwissProt ID: Q84LM4 (Q84LM4)

Gene Name: AARE

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. Can degrade the glycated RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) protein but not the native protein. May be involved in the elimination of glycated proteins (PubMed:12966075). Plays a homeostatic role in sustaining the cytoplasmic antioxidative system. May contribute to the elimination of the oxidized proteins in the cytoplasm (PubMed:22398639)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011042 6-blade_b-propeller_TolB-like
IPR045550 AARE_N
IPR029058 AB_hydrolase_fold
IPR001375 Peptidase_S9_cat

The S-nitrosylation sites of Q84LM4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 314 NLTKSISSGF C PRFSKDGKFL   
2 370 NIVDVIQVVN C PKDGCFPGLY