Protein Name:
Mitofusin-1
|
UniprotKB/SwissProt ID: Q811U4 (Q811U4)
Gene Name:
Mfn1
Organism: Mus musculus (Mouse)
Function: Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12527753, PubMed:15297672, PubMed:23921378, PubMed:24513856). Membrane clustering requires GTPase activity (By similarity). It may involve a major rearrangement of the coiled coil domains (PubMed:15297672). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12527753). Overexpression induces the formation of mitochondrial networks (in vitro). Has low GTPase activity (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion outer membrane
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of Q811U4
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
681 |
QEMATTFARL C QQVDVTQKHL |
CCCCCCHHHH H HHHHHHHHHH |
1.9% |
21278135
|
|
