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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 12

UniprotKB/SwissProt ID: Q811B3 (Q811B3)

Gene Name: Adamts12

Organism: Mus musculus (Mouse)

Function: Metalloprotease that plays a role in the degradation of COMP (By similarity). Also cleaves alpha-2 macroglobulin and aggregan. Has anti-tumorigenic properties (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013273 ADAMTS/ADAMTS-like
IPR050439 ADAMTS_ADAMTS-like
IPR041645 ADAMTS_CR_2
IPR045371 ADAMTS_CR_3
IPR010294 ADAMTS_spacer1
IPR024079 MetalloPept_cat_dom_sf
IPR001590 Peptidase_M12B
IPR002870 Peptidase_M12B_N
IPR010909 PLAC
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf