Protein Name:
Hyaluronan and proteoglycan link protein 4
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UniprotKB/SwissProt ID: Q80WM4 (Q80WM4)
Gene Name:
Hapln4
Organism: Mus musculus (Mouse)
Function: Essential for the proper localization of brevican (BCAN), mainly as a perineuronal nets (PNNs)-type deposition in the brainstem and cerebellum thereby playing a key role in the formation and structural organization of PNNs (PubMed:22121037). Contributes to the formation and transmission of inhibitory GABAergic synapses between Purkinje cells and deep cerebellar nuclei neurons (PubMed:30125937)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q80WM4
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
210 |
HAAWRDGLDW C NAGWLRDGSV |
CCCCCCHHHH H HHHHHHHHHH |
2.2% |
22588120
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| 2 |
264 |
HNAEERYDAF C FTSNLPGRVF |
CCCCCCHHHH H HHHHHHHHHH |
3.79% |
22588120
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