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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Mitochondrial translation release factor in rescue

UniprotKB/SwissProt ID: Q80VP5 (Q80VP5)

Gene Name: Mtrfr

Organism: Mus musculus (Mouse)

Function: Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation. As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR052405 Mito_Transl_Release_Factor
IPR000352 Pep_chain_release_fac_I
IPR045853 Pep_chain_release_fac_I_sf