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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tectonin beta-propeller repeat-containing protein 1

UniprotKB/SwissProt ID: Q80VP0 (Q80VP0)

Gene Name: Tecpr1

Organism: Mus musculus (Mouse)

Function: Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006624 Beta-propeller_rpt_TECPR
IPR006614 Peroxin/Ferlin
IPR011993 PH-like_dom_sf
IPR010482 TECPR1-like_DysF
IPR051513 Tectonin_beta-propeller

The S-nitrosylation sites of Q80VP0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 480 KAPETSRSDE C RGPASTPAEL