UniprotKB/SwissProt ID: Q80TY5 (Q80TY5)
Gene Name:
Vps13b
Organism: Mus musculus (Mouse)
Function: Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Binds phosphatidylinositol 3-phosphate (PubMed:30962439). Functions as a tethering factor in the slow endocytic recycling pathway, to assist traffic between early and recycling endosomes (By similarity). Involved in the transport of proacrosomal vesicles to the nuclear dense lamina (NDL) during spermatid development (PubMed:31218450). Plays a role in the assembly of the Golgi apparatus, possibly by mediating trafficking to the Golgi membrane (By similarity). Plays a role in the development of the nervous system, and may be required for neuron projection development (PubMed:31495077). May also play a role during adipose tissue development (By similarity). Required for maintenance of the ocular lens (PubMed:32915983). Required for proper organization of the Golgi (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Recycling endosome membrane. Cytoplasmic vesicle, secretory vesicle, acrosome membrane. Golgi apparatus, cis-Golgi network membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus, trans-Golgi network membrane. Early endosome membrane. Lysosome membrane
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