UniprotKB/SwissProt ID: Q80TH2 (Q80TH2)
Gene Name:
Erbin
Organism: Mus musculus (Mouse)
Function: Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated ERBB2 'Tyr-1248' receptor, it may contribute to stabilize this unphosphorylated state (By similarity). Inhibits NOD2-dependent NF-kappa-B signaling and pro-inflammatory cytokine secretion (PubMed:16203728)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, hemidesmosome. Nucleus membrane. Basolateral cell membrane
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