Protein Name:
Ectopic P granules protein 5 homolog
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UniprotKB/SwissProt ID: Q80TA9 (Q80TA9)
Gene Name:
Epg5
Organism: Mus musculus (Mouse)
Function: Involved in autophagy. May play a role in a late step of autophagy, such as clearance of autophagosomal cargo. Plays a key role in innate and adaptive immune response triggered by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides from pathogens, and mediated by the nucleotide-sensing receptor TLR9. It is necessary for the translocation of CpG dinucleotides from early endosomes to late endosomes and lysosomes, where TLR9 is located
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, perinuclear region. Lysosome
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR051436
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Autophagy-related_EPG5 |
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The S-nitrosylation sites of Q80TA9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1746 |
FIQLYERVVT C LREDNSDVIF |
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