Protein Name:
Tectonin beta-propeller repeat-containing protein 1
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UniprotKB/SwissProt ID: Q7Z6L1 (Q7Z6L1)
Gene Name:
TECPR1
Organism: Homo sapiens (Human)
Function: Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q7Z6L1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1164 |
SAPPEAHGPV C C--------- |
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| 2 |
1165 |
APPEAHGPVC C ---------- |
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| 3 |
462 |
RTAEDTVEDA C PAEGSREARP |
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