Protein Name:
Interferon regulatory factor 2-binding protein 2
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UniprotKB/SwissProt ID: Q7Z5L9 (Q7Z5L9)
Gene Name:
IRF2BP2
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities (PubMed:12799427). Represses the NFAT1-dependent transactivation of NFAT-responsive promoters (PubMed:21576369). Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles (PubMed:20702774). Plays a role in immature B-cell differentiation (PubMed:27016798)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR044882
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I2BP1/2_C3HC4-RING_sf |
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IPR022750
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Interferon_reg_fac2-bd1_2_Znf |
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