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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Retinoic acid-induced protein 1

UniprotKB/SwissProt ID: Q7Z5J4 (Q7Z5J4)

Gene Name: RAI1

Organism: Homo sapiens (Human)

Function: Transcriptional regulator of the circadian clock components: CLOCK, BMAL1, BMAL2, PER1/3, CRY1/2, NR1D1/2 and RORA/C. Positively regulates the transcriptional activity of CLOCK a core component of the circadian clock. Regulates transcription through chromatin remodeling by interacting with other proteins in chromatin as well as proteins in the basic transcriptional machinery. May be important for embryonic and postnatal development. May be involved in neuronal differentiation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR034732 EPHD
IPR052440 Trans_Reg/Chrom_Remod
IPR001965 Znf_PHD
IPR013083 Znf_RING/FYVE/PHD

The S-nitrosylation sites of Q7Z5J4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 322 QHYGQQGQGY C QPDAAVRTPE   
2 532 EDPLERSFLY C NQARGSPARV