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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Pogo transposable element with ZNF domain

UniprotKB/SwissProt ID: Q7Z3K3 (Q7Z3K3)

Gene Name: POGZ

Organism: Homo sapiens (Human)

Function: Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms (PubMed:20562864). Promotes the repair of DNA double-strand breaks through the homologous recombination pathway (PubMed:26721387)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Chromosome. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR004875 DDE_SF_endonuclease_dom
IPR009057 Homeodomain-like_sf
IPR006600 HTH_CenpB_DNA-bd_dom
IPR050527 Snail/Krueppel_Znf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

The S-nitrosylation sites of Q7Z3K3

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1267 CSSKIQPLDV C IKRTVKNFLH