Protein Name:
Myb-binding protein 1A
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UniprotKB/SwissProt ID: Q7TPV4 (Q7TPV4)
Gene Name:
Mybbp1a
Organism: Mus musculus (Mouse)
Function: May activate or repress transcription via interactions with sequence specific DNA-binding proteins (PubMed:11956195, PubMed:14744933, PubMed:9447996). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (PubMed:14744933). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (PubMed:19129230). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (PubMed:19129230). Has a role in rRNA biogenesis together with PWP1 (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus, nucleolus. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q7TPV4
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1028 |
PSRPRHQAQA C LMLQKTLSAR |
CCCCCCCCCC C CCCHHHHHHC |
1.2% |
20925432
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| 2 |
1043 |
KTLSARELRV C FEDPEWEQLI |
CCCCCCCCCC C CCCHHHHHHC |
2.21% |
20925432
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| 3 |
361 |
STYVGTFLEG C QDDPKRQLTM |
CCCCCCCCCC C CCCHHHHHHC |
2.68% |
20925432
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| 4 |
612 |
LHIFKSPAES C DVLGDIQTCI |
CCCCCCCCCC C CCCHHHHHHC |
2.93% |
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| 5 |
676 |
QVVRSVFGHI C PHLTPRCLQL |
CCCCCCCCCC C CCCHHHHHHC |
1.12% |
20925432
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| 6 |
890 |
MHHLCRARRY C HEVGPCAEAL |
CCCCCCCCCC C CCCHHHHHHC |
1.78% |
20925432
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| 7 |
896 |
ARRYCHEVGP C AEALHAQVER |
CCCCCCCCCC C CCCHHHHHHC |
4.37% |
20925432
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