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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Phospholipid phosphatase-related protein type 4

UniprotKB/SwissProt ID: Q7TME0 (Q7TME0)

Gene Name: Plppr4

Organism: Mus musculus (Mouse)

Function: Postsynaptic density membrane protein that indirectly regulates glutamatergic synaptic transmission through lysophosphatidic acid (LPA)-mediated signaling pathways (PubMed:19766573). Binds lysophosphatidic acid (LPA) and mediates its internalization into cells (PubMed:26671989). Could act as receptor or a transporter of this lipid at the post-synaptic membrane (PubMed:19766573, PubMed:26671989). Modulates lysophosphatidic acid (LPA) activity in neuron axonal outgrowth during development by attenuating phospholipid-induced axon collapse (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Postsynaptic density membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036938 P_Acid_Pase_2/haloperoxi_sf
IPR000326 P_Acid_Pase_2/haloperoxidase
IPR043216 PA_PP_rel

The S-nitrosylation sites of Q7TME0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 569 WLKAAEKTVA C NRSNNQPRIM   
2 605 PKNAEGSTVT C TGSIRYKTLT