Protein Name:
Zinc finger CCCH domain-containing protein 14
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UniprotKB/SwissProt ID: Q7TMD5 (Q7TMD5)
Gene Name:
Zc3h14
Organism: Rattus norvegicus (Rat)
Function: RNA-binding protein involved in the biogenesis of circular RNAs (circRNAs), which are produced by back-splicing circularization of pre-mRNAs. Acts by binding to both exon-intron boundary and 3'-UTR of pre-mRNAs to promote circRNA biogenesis through dimerization and the association with the spliceosome. Required for spermatogenesis via involvement in circRNA biogenesis. Regulates the pre-mRNA processing of ATP5MC1; preventing its degradation. Also binds the poly(A) tail of mRNAs; controlling poly(A) length in neuronal cells
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus speckle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q7TMD5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
652 |
KYDAKCTKAD C PFTHMSRRGP |
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