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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Synaptic vesicle glycoprotein 2B

UniprotKB/SwissProt ID: Q7L1I2 (Q7L1I2)

Gene Name: SV2B

Organism: Homo sapiens (Human)

Function: Probably plays a role in the control of regulated secretion in neural and endocrine cells (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction (PubMed:29649119). Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasmic vesicle, secretory vesicle, acrosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR055415 LD_SV2
IPR011701 MFS
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR005829 Sugar_transporter_CS
IPR022308 SV2

The S-nitrosylation sites of Q7L1I2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 141 FALPSAEKDM C LSSSKKGMLG