Protein Name:
Lon protease homolog, mitochondrial
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UniprotKB/SwissProt ID: Q7KUT2 (Q7KUT2)
Gene Name:
Lon
Organism: Drosophila melanogaster (Fruit fly)
Function: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner. Regulates mitochondrial DNA (mtDNA) copy number and transcription by stabilizing the mitochondrial TFAM:mtDNA ratio via selective degradation of TFAM
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix
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Graphical Visualization of S-nitrosylation Sites:
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