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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

UniprotKB/SwissProt ID: Q7K5K3 (Q7K5K3)

Gene Name: Pdhb

Organism: Drosophila melanogaster (Fruit fly)

Function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity). Might play a role in regulating synapse structure formation at neuromuscular junctions (PubMed:29501567). Might play a role in maintenance of mitochondrial morphology (PubMed:29501567)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027110 PDHB_mito-type
IPR029061 THDP-binding
IPR009014 Transketo_C/PFOR_II
IPR005475 Transketolase-like_Pyr-bd
IPR033248 Transketolase_C