Protein Name:
Methionine-R-sulfoxide reductase B2, mitochondrial
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UniprotKB/SwissProt ID: Q78J03 (Q78J03)
Gene Name:
Msrb2
Organism: Mus musculus (Mouse)
Function: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q78J03
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
132 |
ILRRLDTSLG C PRMEVVCKQC |
CHHHHHHHCC C CCCCCCCCCC |
2.04% |
21278135
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| 2 |
162 |
DGPKPTGQRF C INSVALKFKP |
CHHHHHHHCC C CCCCCCCCCC |
2.91% |
21278135
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