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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Zinc transporter ZIP4

UniprotKB/SwissProt ID: Q78IQ7 (Q78IQ7)

Gene Name: Slc39a4

Organism: Mus musculus (Mouse)

Function: Selective transporter that mediates the uptake of Zn(2+) (PubMed:12801924, PubMed:14612438, PubMed:14709598). Plays an essential role for dietary zinc uptake from small intestine (PubMed:12801924). The Zn(2+) uniporter activity is regulated by zinc availability (By similarity). Also exhibits polyspecific binding and transport of Cu(2+), Cd(2+) and possibly Ni(2+) but at higher concentrations (PubMed:12801924)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Recycling endosome membrane. Apical cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003689 ZIP
IPR049406 ZIP4_12_EF-hand
IPR041137 ZIP4_N
IPR050799 ZIP_Transporter