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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: La-related protein 4

UniprotKB/SwissProt ID: Q71RC2 (Q71RC2)

Gene Name: LARP4

Organism: Homo sapiens (Human)

Function: RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120). Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120). Plays a role in the regulation of mRNA translation (PubMed:21098120). Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987, PubMed:27615744)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, Stress granule. Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR045180 La_dom_prot
IPR006630 La_HTH
IPR034903 LARP4_RRM
IPR035979 RBD_domain_sf
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf

The S-nitrosylation sites of Q71RC2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 130 KECLKKQLEF C FSRENLSKDL   
2 599 KPSRASTASP C NNNINAATAV   
3 76 KEYEVMYSSS C ETTRNTTGIE