Protein Name:
Filamin-binding LIM protein 1
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UniprotKB/SwissProt ID: Q71FD7 (Q71FD7)
Gene Name:
Fblim1
Organism: Mus musculus (Mouse)
Function: Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q71FD7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
248 |
YQDTLEKCGK C GEVVQEHVIR |
CCCCCCHHHC C EEEEEECCCC |
3.22% |
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| 2 |
334 |
ECMGRNFHEN C YRCEDCSVLL |
CCCCCCHHHC C EEEEEECCCC |
1.75% |
21278135
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| 3 |
35 |
AVSEEVGQAA C EARRARPWEM |
CCCCCCHHHC C EEEEEECCCC |
4.75% |
21278135
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