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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Syntaxin-binding protein 4

UniprotKB/SwissProt ID: Q6ZWJ1 (Q6ZWJ1)

Gene Name: STXBP4

Organism: Homo sapiens (Human)

Function: Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001478 PDZ
IPR051342 PDZ_scaffold
IPR036034 PDZ_sf
IPR001202 WW_dom
IPR036020 WW_dom_sf

The S-nitrosylation sites of Q6ZWJ1

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 58 YIQEIIPGGD C YKDGRLKPGD