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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Rho GTPase-activating protein SYDE1

UniprotKB/SwissProt ID: Q6ZW31 (Q6ZW31)

Gene Name: SYDE1

Organism: Homo sapiens (Human)

Function: GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1 (PubMed:27917469)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000008 C2_dom
IPR052118 Rho-GAP_regulator
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom

The S-nitrosylation sites of Q6ZW31

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 665 WSVCGRDFLP C GRDFLSGPDY