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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: FYVE, RhoGEF and PH domain-containing protein 6

UniprotKB/SwissProt ID: Q6ZV73 (Q6ZV73)

Gene Name: FGD6

Organism: Homo sapiens (Human)

Function: May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR035899 DBL_dom_sf
IPR000219 DH_dom
IPR037743 FGD6_N_PH
IPR051092 FYVE_RhoGEF_PH
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000306 Znf_FYVE
IPR017455 Znf_FYVE-rel
IPR013083 Znf_RING/FYVE/PHD

The S-nitrosylation sites of Q6ZV73

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 405 QDLVNSQKAM C NETTSFEKMA