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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Rho family-interacting cell polarization regulator 1

UniprotKB/SwissProt ID: Q6ZS17 (Q6ZS17)

Gene Name: RIPOR1

Organism: Homo sapiens (Human)

Function: Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Golgi apparatus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR031780 FAM65_N
IPR026136 RIPOR3

The S-nitrosylation sites of Q6ZS17

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 196 RGHREYTESM C LLESELEAQL   
2 984 FWDQCTERLS C FLCPVERVLL