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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Helicase SRCAP

UniprotKB/SwissProt ID: Q6ZRS2 (Q6ZRS2)

Gene Name: SRCAP

Organism: Homo sapiens (Human)

Function: Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR017956 AT_hook_DNA-bd_motif
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C-like
IPR014012 HSA_dom
IPR050520 INO80/SWR1_helicase
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR049730 SNF2/RAD54-like_C
IPR000330 SNF2_N

The S-nitrosylation sites of Q6ZRS2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 2246 KQTHILEQAL C RAEDEEDIRA   
2 2372 EGPGAGDESS C GTGGGTHRRS   
3 265 LTSSKAGSSP C LGSSSAASSP