Protein Name:
Dynamin-binding protein
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UniprotKB/SwissProt ID: Q6XZF7 (Q6XZF7)
Gene Name:
DNMBP
Organism: Homo sapiens (Human)
Function: Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells (PubMed:17015620, PubMed:19767742). Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation (PubMed:20479467). Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Golgi apparatus, Golgi stack. Cytoplasm, cytoskeleton. Synapse. Cell junction
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6XZF7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1134 |
RFDKLLDFYN C TERAEKLKDK |
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| 2 |
120 |
WGARGFFPSS C VRELCLSSQS |
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| 3 |
1413 |
PQDASPPPKE C DQGTLSASLN |
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| 4 |
1434 |
PSNSESSPSR C PSDPDSTSQP |
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| 5 |
327 |
LARIPETSLD C LENTLGVEEQ |
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