Protein Name:
Nicotinate phosphoribosyltransferase
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UniprotKB/SwissProt ID: Q6XQN6 (Q6XQN6)
Gene Name:
NAPRT
Organism: Homo sapiens (Human)
Function: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate (PubMed:17604275, PubMed:21742010, PubMed:26042198). Helps prevent cellular oxidative stress via its role in NAD biosynthesis (PubMed:17604275)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6XQN6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
101 |
AFFEHLRALD C SEVTVRALPE |
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| 2 |
385 |
VIGIGTSVVT C PQQPSLGGVY |
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| 3 |
463 |
RVWPPGAQEP C TVRPAQVEPL |
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| 4 |
477 |
PAQVEPLLRL C LQQGQLCEPL |
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| 5 |
533 |
ERLQALVNSL C AGQSP----- |
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