Protein Name:
Myosin phosphatase Rho-interacting protein
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UniprotKB/SwissProt ID: Q6WCQ1 (Q6WCQ1)
Gene Name:
MPRIP
Organism: Homo sapiens (Human)
Function: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6WCQ1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
438 |
DLDGEIDLSA C YDVTEYPVQR |
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| 2 |
503 |
SLPEEKNKSS C SFETCPRPTE |
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