UniprotKB/SwissProt ID: Q6VUC0 (Q6VUC0)
Gene Name:
TFAP2E
Organism: Homo sapiens (Human)
Function: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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