UniprotKB/SwissProt ID: Q6UXB2 (Q6UXB2)
Gene Name:
CXCL17
Organism: Homo sapiens (Human)
Function: Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells (PubMed:16455961, PubMed:23115081). Plays a role in angiogenesis and possibly in the development of tumors (PubMed:16989774, PubMed:23115081). Acts as an anti-inflammatory in the stomach (PubMed:23115081). May play a role in the innate defense against infections (PubMed:17307946). Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions (PubMed:25411203) Seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted
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