UniprotKB/SwissProt ID: Q6TLJ0 (Q6TLJ0)
Gene Name:
DRD4
Organism: Mustela putorius furo (European domestic ferret)
Function: Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs. Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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