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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: SHC-transforming protein 4

UniprotKB/SwissProt ID: Q6S5L8 (Q6S5L8)

Gene Name: SHC4

Organism: Homo sapiens (Human)

Function: Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Postsynaptic cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR051235 CEP152/SHC-Transforming
IPR011993 PH-like_dom_sf
IPR006019 PID_Shc-like
IPR006020 PTB/PI_dom
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR035676 SHC_SH2

The S-nitrosylation sites of Q6S5L8

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 526 HIKQQLWSEE C YHGKLSRKAA