Protein Name:
Toll-like receptor 13
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UniprotKB/SwissProt ID: Q6R5N8 (Q6R5N8)
Gene Name:
Tlr13
Organism: Mus musculus (Mouse)
Function: Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus; however, these data require additional evidences
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endosome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6R5N8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
527 |
KLQSLILSHN C LKILEPNSFS |
CCHHHHHHHH C CCCCCEEEEE |
3.24% |
21278135
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