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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Acyl-coenzyme A thioesterase 5

UniprotKB/SwissProt ID: Q6Q2Z6 (Q6Q2Z6)

Gene Name: Acot5

Organism: Mus musculus (Mouse)

Function: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16940157). Mainly active on medium-chain acyl-CoAs (PubMed:15007068). Seems to be involved in intraperoxisomal regulation of acyl-CoA levels, but not CoASH levels (PubMed:15007068). May have a function in termination of beta-oxidation of fatty acids (PubMed:15007068)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Peroxisome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR029058 AB_hydrolase_fold
IPR016662 Acyl-CoA_thioEstase_long-chain
IPR014940 BAAT_C
IPR006862 Thio_Ohase/aa_AcTrfase
IPR042490 Thio_Ohase/BAAT_N

The S-nitrosylation sites of Q6Q2Z6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 14 TVSLEPTGHS C WDEPLSIAVR