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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytosolic non-specific dipeptidase

UniprotKB/SwissProt ID: Q6Q0N1 (Q6Q0N1)

Gene Name: Cndp2

Organism: Rattus norvegicus (Rat)

Function: Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way (By similarity). Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001261 ArgE/DapE_CS
IPR017153 CNDP/DUG1
IPR051458 Cyt/Met_Dipeptidase
IPR002933 Peptidase_M20
IPR011650 Peptidase_M20_dimer

The S-nitrosylation sites of Q6Q0N1

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 192 DKFFKDVDYV C ISDNYWLGKN   
2 300 DVGAGTLLHS C KKDILMHRWR