Protein Name:
Neutral cholesterol ester hydrolase 1
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UniprotKB/SwissProt ID: Q6PIU2 (Q6PIU2)
Gene Name:
NCEH1
Organism: Homo sapiens (Human)
Function: Hydrolyzes 2-acetyl monoalkylglycerol ether (1-O-alkyl-2-acetyl-sn-glycerol), the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (PubMed:17052608). May be responsible for the hydrolysis of cholesterol esters (such as cholesteryl (9Z-octadecenoate)) in macrophages (By similarity). Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds (By similarity). May contribute to cancer pathogenesis by promoting tumor cell migration (PubMed:17052608)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Microsome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6PIU2
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
186 |
QKYMVDPGRI C ISGDSAGGNL |
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| 2 |
345 |
QLLPKTYILT C EHDVLRDDGI |
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