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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Aspartate--tRNA ligase, mitochondrial

UniprotKB/SwissProt ID: Q6PI48 (Q6PI48)

Gene Name: DARS2

Organism: Homo sapiens (Human)

Function: Catalyzes the attachment of aspartate to tRNA(Asp) in a two-step reaction: aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix. Mitochondrion membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR004364 Aa-tRNA-synt_II
IPR006195 aa-tRNA-synth_II
IPR045864 aa-tRNA-synth_II/BPL/LPL
IPR004524 Asp-tRNA-ligase_1
IPR047089 Asp-tRNA-ligase_1_N
IPR002312 Asp/Asn-tRNA-synth_IIb
IPR047090 AspRS_core
IPR004115 GAD-like_sf
IPR029351 GAD_dom
IPR012340 NA-bd_OB-fold
IPR004365 NA-bd_OB_tRNA

The S-nitrosylation sites of Q6PI48

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 152 KVKTAELLNA C KKLPFEIKNF   
2 371 SKPHGTVKAI C IPEGAKYLKR   
3 449 LLTAGEHNKA C SLLGKLRLEC   
4 459 CSLLGKLRLE C ADLLETRGVV   
5 69 SSHLGQEVTL C GWIQYRRQNT