UniprotKB/SwissProt ID: Q6PB93 (Q6PB93)
Gene Name:
Galnt2
Organism: Mus musculus (Mouse)
Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region (By similarity). Involved in O-linked glycosylation of APOC-III, ANGPTL3 and PLTP. It participates in the regulation of HDL-C metabolism (PubMed:27508872)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus, Golgi stack membrane. Secreted
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