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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tryptophan--tRNA ligase, cytoplasmic

UniprotKB/SwissProt ID: Q6P7B0 (Q6P7B0)

Gene Name: Wars1

Organism: Rattus norvegicus (Rat)

Function: Catalyzes the attachment of tryptophan to tRNA(Trp) in a two-step reaction: tryptophan is first activated by ATP to form Trp-AMP and then transferred to the acceptor end of the tRNA(Trp). Could also possess an angiostatic activity

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001412 aa-tRNA-synth_I_CS
IPR002305 aa-tRNA-synth_Ic
IPR014729 Rossmann-like_a/b/a_fold
IPR002306 Trp-tRNA-ligase
IPR009068 uS15_NS1_RNA-bd_sf
IPR000738 WHEP-TRS_dom

The S-nitrosylation sites of Q6P7B0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 309 KIFRDRTDIQ C LIPCAIDQDP   
2 313 DRTDIQCLIP C AIDQDPYFRM